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Exploration and Phytochemical Estimation of Murraya koenigii Leaves for Pharmaceutical Applications

By: Sharma, Radheshyam.
Contributor(s): Umesh Kumar.
Publisher: Raipur Asian Pharma Press 2019Edition: Vol.9(3), July-Sep.Description: 159-168p.Subject(s): PHARMACEUTICSOnline resources: Click here In: Asian journal of pharmaceutical researchSummary: The aim of current study was to evaluate so many pharmaceutical properties in the world of medicine. The purpose of the current study was to investigate the various phytochemicals present in Murraya koenigii leafs. The preliminary phytochemical studies with the help of Thin layer chromatography (TLC) method revealed that petroleum ether fraction contains volatile oil. The benzene fraction showed presence of fixed oil and alkaloid. Acetone fraction has confirmed presence of alkaloid. The fractions were further subjected to TLC in toluene: ethyl acetate (93:7) & ethyl acetate: methanol: water (76.5: 13.5: 10) solvent system with different detecting reagents for further confirmation of phytoconstituents. The alkaloid was prominently found in benzene, chloroform, acetone and methanol extract. The petroleum extract was found to contain volatile oil and fixed oil in benzene extract. The proximate analysis revealed that moisture content was 15%, total ash 73.33%, acid insoluble ash 26%, sulphated ash 80%, water soluble ash 89.5%, water insoluble ash 10.5%, acid soluble ash 74%. Several potent antioxidant compounds were extracted and their presences are confirmed by structure elucidation through various spectroscopic methods.
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The aim of current study was to evaluate so many pharmaceutical properties in the world of medicine. The purpose of the current study was to investigate the various phytochemicals present in Murraya koenigii leafs. The preliminary phytochemical studies with the help of Thin layer chromatography (TLC) method revealed that petroleum ether fraction contains volatile oil. The benzene fraction showed presence of fixed oil and alkaloid. Acetone fraction has confirmed presence of alkaloid. The fractions were further subjected to TLC in toluene: ethyl acetate (93:7) & ethyl acetate: methanol: water (76.5: 13.5: 10) solvent system with different detecting reagents for further confirmation of phytoconstituents. The alkaloid was prominently found in benzene, chloroform, acetone and methanol extract. The petroleum extract was found to contain volatile oil and fixed oil in benzene extract. The proximate analysis revealed that moisture content was 15%, total ash 73.33%, acid insoluble ash 26%, sulphated ash 80%, water soluble ash 89.5%, water insoluble ash 10.5%, acid soluble ash 74%. Several potent antioxidant compounds were extracted and their presences are confirmed by structure elucidation through various spectroscopic methods.

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